Global Update on Prion Diseases: What does the latest Epidemiological Atlas tell us?

Authors: Paula Marco and Nerea Larrañaga Human prion diseases (such as Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI) and Gerstmann-Sträussler-Scheinker syndrome (GSS), among others) are a group of rapidly progressive, fatal and potentially transmissible neurodegenerative disorders caused by the misfolding of the physiological protein PrPC, which results in the misfolding of the protein PrPC.

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