Amyotrophic Lateral Sclerosis joins the group of diseases known as prion-like diseases.
Author: Jorge Moreno Charco Prion diseases, or Transmissible Spongiform Encephalopathies (TSE), could be defined as a group of neurodegenerative diseases related to the misfolding and propagation of the endogenous prion protein through the central nervous system. This misfolded protein, in addition to spreading uncontrollably through the patient's brain, is highly neurotoxic, which can lead to a [...]
Research priorities on the role of α-synuclein in the pathogenesis of Parkinson's Disease
Authors: Nerea Larrañaga and Paula Marco Scientists from the International Parkinson and Movement Disorders Society (MDS) have published a paper highlighting the main research priorities for α-synuclein (αSyn) protein research in Parkinson's disease. This review, led by an international team of experts, focuses on addressing key aspects of α-synuclein [...]
Global Update on Prion Diseases: What does the latest Epidemiological Atlas tell us?
Authors: Paula Marco and Nerea Larrañaga Human prion diseases (such as Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI) and Gerstmann-Sträussler-Scheinker syndrome (GSS), among others) are a group of rapidly progressive, fatal and potentially transmissible neurodegenerative disorders caused by the misfolding of the physiological protein PrPC, which results in the misfolding of the protein PrPC.
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