Category: news

Research priorities on the role of α-synuclein in the pathogenesis of Parkinson's Disease

Authors: Nerea Larrañaga and Paula Marco Scientists from the International Parkinson and Movement Disorders Society (MDS) have published a paper highlighting the main research priorities for α-synuclein (αSyn) protein research in Parkinson's disease. This review, led by an international team of experts, focuses on addressing key aspects of α-synuclein [...]

Global Update on Prion Diseases: What does the latest Epidemiological Atlas tell us?

Authors: Paula Marco and Nerea Larrañaga Human prion diseases (such as Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI) and Gerstmann-Sträussler-Scheinker syndrome (GSS), among others) are a group of rapidly progressive, fatal and potentially transmissible neurodegenerative disorders caused by the misfolding of the physiological protein PrPC, which results in the misfolding of the protein PrPC.

Expansion and reactivation of Ionis PrProfile (ION717) clinical trial for people with symptomatic prion disease

Author: Joaquín Castilla Ionis Pharmaceuticals has just announced that the recruitment pause for its PrProfile (ION717) study for people with symptomatic prion disease has been lifted. Important information to note: Resumption of recruitment: After a planned pause, recruitment for the PrProfile clinical trial has resumed as of [...]

New international study looks for correlations between genetic variations and sporadic CJD

Author: Josu Galarza Scientists from around the world have collaborated on a genetic study that seeks to identify small changes in the genome that may be related to the clinical development and age of onset of sporadic Creutzfeldt-Jakob disease (sCJD). Prion diseases are classified as rare diseases due to their low incidence [...].